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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Hypertension. 2017 Mar 13;69(5):950–956. doi: 10.1161/HYPERTENSIONAHA.116.08952

Figure 3. The Relationship Between Autonomous Aldosterone Secretion, Renin, and Urinary Sodium-to-Potassium Excretion.

Figure 3

Autonomous aldosterone secretion is represented by tertiles of the 24h urinary aldosterone excretion rate measured on a liberalized dietary sodium intervention. Renin activity is represented by tertiles of renin when sodium restricted, whereby an inability to stimulate renin serves as a surrogate for excessive MR activity. The figure displays the interaction between the independent variables, aldosterone secretion and renin activity, and the dependent variable, urinary sodium-to-potassium excretion ratio. Bars represent the mean value in each tertile. The adjusted interaction model is adjusted for age, sex, race, body-mass index, and systolic blood pressure. (AER=24h aldosterone excretion rate; PRA=plasma renin activity)