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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Magn Reson Med. 2016 Oct 13;78(3):1087–1092. doi: 10.1002/mrm.26482

Figure 1.

Figure 1

With a constant slice-select gradient, hyperpolarized signal is overestimated after the initial RF pulse because of excess signal in the transition band, regardless of the flip angle scheme (A,D,G). By scaling the slice-select gradient, the desired signal response can be achieved (B,E,H). The amount of excess signal is a function of the flip angle and RF excitation profile (C,F,I). RF flip angle used in each case: constant 30° (A-C); RF variable flip angle (D-F); RF and diffusion variable flip angle (G-I).