| Health System Factors | ||||||
| State substitution laws | Availability of samples | Insurance companies | Availability of generics | Performance metrics | ||
| Workflow Factors | ||||||
| Practice disruption | Default to generic | Pharmacy | Insurance | Formulary | Generic nomenclature | Point of care IT tools |
| Provider Factors | ||||||
| Attitude towards generics | Lack of trusted sources | Reluctance to switch patient medication | Level of knowledge about generics | Accessibility of information about generics | Multiple generic brands | Specialists |
| Patient Factors | ||||||
| Cost | Preference | Prior experience | Side effects | DTC advertising | Pill and package | |