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. 2017 Mar 30;19(3):e93. doi: 10.2196/jmir.6971

Table 2.

Multivariate analysis of vancomycin knowledge survey responses (N=577).

Topic		Profession				Experience or confidence^a
Topic		Nurse ref^b	Doctor	Pharmacist	1 ref^b		2	3	4
Loading dose	OR^c (95% CI)	-	2.6 (1.7-4.1)	16.8 (7.9-35.7)	-		1.4 (0.8-2.7)	4.6 (2.4-8.6)	11.1 (3.3-36.9)
Loading dose	P value	-	<.001	<.001	-		.25	<.001	<.001
Maint dose^d	OR (95% CI)	-	2.5 (1.7-3.8)	12.1 (5.9-24.7)	-		1.0 (0.6-1.8)	2.2 (1.2-3.8)	3.3 (1.1-9.6)
Maint dose^d	P value	-	<.001	<.001	-		.85	.006	.03
Admin rate^e	OR (95% CI)	-	1.0 (0.6-1.4)	2.9 (1.3-6.4)	-		2.1 (1.4-3.3)	4.7 (2.9-7.6)	5.7 (0.2-1.1)
Admin rate^e	P value	-	.82	.01	-		.001	<.001	<.001
Level timing^f	OR (95% CI)	-	2.7 (1.9-4.1)	8.5 (4.0-17.7)	-		3.6 (2.1-5.9)	6.8 (4.0-11.6)	4.0 (1.4-10.9)
Level timing^f	P value	-	<.001	<.001	-		<.001	<.001	.008
Trough range^g	OR (95% CI)	-	3.9 (2.5-6.1)	5.6 (2.1-15.1)	-		3.4 (2.1-5.6)	5.7 (3.2-10.0)	5.7 (1.2-26.5)
Trough range^g	P value	-	<.001	.001	-		<.001	<.001	.03
Total correct^h	bⁱ (95% CI)	-	.8 (0.6-1.1)	1.7 (1.4-2.1)	-		.9^j (1.4-2.1)
Total correct^h	P value	-	<.001	<.001	-		<.001

^aExperience or confidence: 1, none; 2, a little; 3, moderate; 4, very experienced or confident.

^bref: reference group for multivariate analysis.

^cOR: odds ratio.

^dmaint dose: maintenance dose.

^eadmin rate: administration rate.

^flevel timing: timing of first level.

^gtrough range: target range for plasma trough level.

^htotal correct: nurse (all levels), doctor (all levels), pharmacist (all levels).

ⁱb: regression coefficient.

^jAverage of responses to three vancomycin experience or confidence questions, therefore a multiple regression was performed for total correct.