FIG 6.
Effect of NPQ202A on gene editing. (A) Schematic diagram of the minireplicon assay for examining gene editing efficiency. An hPIV2 editing signal was added in the Rluc gene of the hPIV2-Rluc-Fluc minigenome. The translated amino acid sequences are shown. After GG is added by hPIV2 RdRp, the resulting sequence can be converted to the Rluc open reading frame. (B) Intrinsic editing efficiency. The calculation method is described in the text. Data represent means and standard deviations from triplicate experiments.