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. 2017 Apr 13;91(9):e02425-16. doi: 10.1128/JVI.02425-16

FIG 4.

FIG 4

Relative levels of resistance of HIV-1 cell-to-cell infection to neutralization is reflected in diminished potency and efficacy of bNAbs. (A) The table indicates the degree to which cell-to-cell infection is less efficiently neutralized than cell-free infection, indicating the fold increase in the 50% inhibitory concentration for each antibody-virus combination tested. Numbers represent mean values of results from duplicates of at least two independent experiments. (B) Maximum efficacy represented by the maximal percentages of inhibition at saturating concentrations of MAbs in cell-to-cell infection and cell-free infection were plotted and compared using a Wilcoxon matched-pair test. P values for the Wilcoxon analysis are indicated for T/F Envs (top) and laboratory-adapted NL4-3 or chronic JR-FL Env (bottom).