TABLE 2.

IC₅₀ and percent maximum neutralization with bNAbs

Strain	bNAb	Value under indicated transmission conditions
		Cell free		Cell to cell
		IC50	% maximum neutralization	IC50	% maximum neutralization
NLCIQH0692	Leu3a	0.01	100	0.02	100
	2G12	2.24	90.5	83.0	35.9a
	VRC01	0.28	93.2	12.6	51.5a
	HJ16	0.56	92.8	34.8	55.3a
	2F5	0.008	91.8	2.8	74.3
	4E10	0.1	95.8	7.4	59.2
	35O22	0.002	97.2	6.9	56.1
	PG9	NAb	NA	NA	NA
	PGT121	0.058	89.1	0.1	69.7
	10-1074	0.02	91.1	0.14	74
	PGT126	0.003	98.9	0.3	80
NLCIRHPA	Leu3a	0.01	100	0.01	100
	2G12	NA	NA	NA	NA
	VRC01	1.3	80a	4.6	66.7a
	HJ16	0.004	96.6	0.17	62.1
	2F5	0.13	90.1	9.5	60.4
	4E10	1.3	99.2	146	55.8a
	35O22	NA	NA	NA	NA
	PG9	5.1	73.5a	>50	38.2a
	PGT121	0.013	96.0	0.16	66.1
	10-1074	0.021	90.3	>25	44.8
	PGT126	0.013	100	>25	42.1
NLCINL4-3	Leu3a	0.03	96.5	0.04	96.4
	2G12	0.1	99.9	3.6	95.5
	VRC01	0.17	96.9	2.1	98.9
	HJ16	0.02	96.6	0.9	97.2
	2F5	0.06	93.1	4.5	99
	4E10	0.3	99.4	5.9	94.5
	35O22	0.01	90.1	0.07	92.9
	PG9	0.36	81.9a	2.5	72a
	PGT121	NA	NA	NA	NA
	10-1074	NA	NA	NA	NA
	PGT126	NA	NA	NA	NA
NLCIJR-FL	Leu3a	0.04	97.7	0.1	94.7
	2G12	0.3	97.8	0.7	90.9
	VRC01	0.04	96.0	0.5	94.7
	HJ16	NA	NA	NA	NA
	2F5	0.03	99.8	1.4	90.1
	4E10	1.0	96.1	9.2	95.6
	35O22	0.002	96.4	1.0	70.1a
	PG9	NA	NA	NA	NA
	PGT121	0.04	99.8	0.03	97.5
	10-1074	0.01	100	0.09	97.4
	PGT126	0.1	100	0.07	100

^aThe maximum percentage of inhibition detected in these assays was not saturated at the highest concentration tested.

^bNA, not active, due to low inhibitory activity.