FIG 6.

HIV-1 particles produced in the presence of C1 contain unstable capsids. HIV-1 particles were concentrated by ultracentrifugation and resuspended, and cores were released by ultracentrifugation of the virions through a layer of nonionic detergent into a sucrose density gradient. Shown is the level of CA present in each fraction, as quantified by p24 ELISA. The results shown are representative of three independent experiments. The fraction 10 dip in CA content was not observed in the other experiments.