FIG 9.

Durability of plasma IgG binding (A) and serum neutralizing (B) antibody responses evaluated as proportion of change per week. Proportion of change per week was calculated as [(response at durability time point − response at peak time point)/response at peak time point]/number of weeks between peak and durability time points and was calculated only for animals that showed a positive response at the peak immunity time point. The midline of the box indicates the median, and the ends of the box indicate the 25th and 75th percentiles. The whiskers that extend from the top and bottom of the box extend to the most extreme data points that are no more than 1.5 times the interquartile range (i.e., the height of the box) or, if no value meets this criterion, to the data extremes. For binding antibody response, AUCs from titration data in BAMA were used for the calculation. ID₅₀ titers were used for neutralization response. Descriptive statistics of these values and results for between-group comparisons are in Table 5.