Table 1.
39 AKU patients show CatD values included between 18,76–185,2 ng/mL (measured with ELISA in serum samples) with a mean and standard deviation 62,54 ± 41,45 ng/mL
| AKU patients | Reference values | |
|---|---|---|
| CysC mg/L (ELISA) | ||
| Samples | 29 M 11 F | --- |
| Min-max | M:0.60–1.00 F:0.40–0.90 |
M:0.71–1.02a
F:0.58–0.98a |
| Mean ± SD | M:0.70 ± 0.15 F:0.71 ± 0.14 |
M:0.86 ± 0.15a
F:0.78 ± 0.20a |
| CatD ng/mL (ELISA) | ||
| Samples | 39 | 12 |
| Min-max | 18.76–185.2 | 36.35–56.72 |
| Mean ± SD | 62.54 ± 41.45 | 46.68 ± 5.88 |
| HGA μM (ELISA) | ||
| Samples | 40 | 8 |
| Min-max | 13.40–54.70 | 0.00 |
| Mean ± SD | 25.89 ± 8.00 | 0.00 |
The outliers 18.76 ng/mL; 19.24 ng/mL and 185.2 ng/mL are responsible for the high values of standard deviation. 12 healthy control show values included between 36,35 and 56,72 ng/mL (measured with ELISA in serum samples) with a mean and standard deviation of 46,68 ± 5,88 ng/mL. 29 AKU male patients show CysC values included between 0,60 mg/L and 1,00 mg/L (measured with ELISA in serum samples) with a mean and standard deviation 0,70 ± 0,15 mg/L, 11 AKU female patients show CysC values included between 0,40 mg/L and 0,90 mg/L (measured with ELISA in serum samples) with a mean and standard deviation 0,71 ± 0,14 mg/L. Reference values differ in many populations and with sex and age: for women, the average reference interval is 0.52 to 0.90 mg/L with a mean of 0.71 mg/L. For men, the average reference interval is 0.56 to 0.98 mg/L with a mean of 0.77 mg/L [11]. 40 AKU patients show HGA values included between 13,40 and 54,70 μM (measured with ELISA in serum samples) with a mean and standard deviation 25,89 ± 8,00 μM. Thanks to correlation matrix we have verified all the possible correlations between HGA and the other biomarkers, but owing to its great variability, all the Pearson’s index show no statistically significant values
a[11]