Table 5.
Top diseases and biological functions associated with differentially methylated genes between smokers vs. non-smokers
| Diseases and disorders | P value | No. of molecules |
| Hereditary disorder | 1.44E-02–8.85E-05 | 3 |
| Organismal injury and abnormalities | 4.84E-02–8.85E-05 | 8 |
| Renal and urological disease | 2.82E-02–8.85E-05 | 2 |
| Cancer | 4.84E-02–3.80E-04 | 8 |
| Cardiovascular disease | 3.45E-02–3.803E-04 | 1 |
| Molecular and cellular functions | P value | No. of molecules |
| Cell morphology | 3.48E-02–3.80E-04 | 2 |
| Cell-to-cell signaling and interaction | 4.07E-02–3.80E-04 | 2 |
| Cellular assembly and organization | 4.44E-02–3.80E-04 | 3 |
| Cell cycle | 3.42E-03–7.61E-04 | 2 |
| Cell death and survival | 4.45E-02–7.61E-04 | 2 |
| Physiological system development and function | P value | No. of molecules |
| Cardiovascular system development and function | 4.07E-02–3.80E-04 | 3 |
| Embryonic development | 3.26E-02–3.80E-04 | 4 |
| Lymphoid tissue structure and development | 6.07E-02–3.80E-04 | 1 |
| Organismal development | 2.67E-02–3.80E-04 | 3 |
| Organ morphology | 2.52E-02–3.80E-04 | 3 |