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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Biomaterials. 2016 Jul 27;105:66–76. doi: 10.1016/j.biomaterials.2016.07.033

Figure 3.

Figure 3

Effect of antibody/ligand density on relative SERS signals. Nanoparticles were conjugated with various amounts of antibodies and compared for their relative SERS signals targeting IMR-90 iPSCs vs. NIH3T3 fibroblasts. (A) Effect of the ligand density on the relative SERS signals from SSEA-5-conjugated nanoparticles targeting IMR-90 iPSCs vs. NIH3T3 fibroblasts. Note: A ligand density of 25 ligands per particle in SSEA-5-conjugated nanoparticles produced the highest signal ratio. (B) Effect of the ligand density on the relative SERS signals from TRA-1-60-conjugated nanoparticles targeting IMR-90 iPSCs vs. NIH3T3 fibroblasts. Note: A ligand density of 100 ligands per particle in TRA-1-60-conjugated nanoparticles produced the highest signal ratio.