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. 2016 Oct 25;28(3):519–527. doi: 10.1093/annonc/mdw560

Figure 2.

Figure 2.

(A) RA-CUSUM analysis of lymph node harvest versus overall survival in chemoradiotherapy plus surgery group (NCRS); lymph node harvest does not affect survival with no discernable pattern to this CUSUM curve. (B) RA-CUSUM analysis of lymph node harvest versus overall survival in chemotherapy plus surgery group (NCS); change point as illustrated by the plateau of curve at 22–52 lymph nodes. Above 52 lymph nodes there were significant improvements in disease-free survival (22–36 months; P = 0.028), and overall recurrence (47.1%–15.9%; P < 0.001) and non-significant improvement in overall survival (27–38 months; P = 0.171).