Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Superposition of the crystal structures of grazoprevir (cyan) and simeprevir (magenta) bound to HCV NS3/4A protease (PDB codes 3SUD and 3KEE). The protein is represented as ribbon, and only residues Arg-123, Asp-168, Arg-155, and Gln-80/Lys-80 that form the salt bridge/hydrogen bonding network are shown (gray, carbon; red, oxygen; blue, nitrogen). The Lys-80 side chain is also highlighted (orange, carbon). The dashed yellow lines represent the distance in angstroms as labeled.
