Table 1.

Potency of grazoprevir against NS3/4A proteases isolated from HCV genotypes

Enzymea	IC50 ± S.D.b
	nm
GT1a (H77; NC_004102)	0.007 ± 0.001
GT1b (BK; M58335)	0.004 ± 0.001
GT2a (JFH1; AB047639)	0.067 ± 0.024
GT2b (J8; D10988)	0.135 ± 0.051
GT3a (NZL1; D17763)	0.690 ± 0.194
GT4a (ED43; GU814265)	0.062 ± 0.031
GT5a (1209A014c)	0.067 ± 0.022
GT6a (6a77; DQ480512)	0.034 ± 0.007

^a The strain and GenBank^TM accession numbers for the HCV reference sequences are indicated in parentheses.

^b The standard deviation is n ≥ 3.

^c This is the patient sequence identifier.