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. 2017 Feb 27;292(15):6269–6280. doi: 10.1074/jbc.M116.764407

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 7. — EZH2 and FBW7 protein levels negatively correlate in pancreatic cancer patient specimens. A, representative images of immunohistochemistry analysis of EZH2 and FBW7 protein expression on tissue microarray (n = 10 normal pancreatic tissue specimens, n = 47 PDAC tissue specimens) tissue sections. B, box plots of EZH2 and FBW7 protein expression based on their staining index in normal pancreatic tissues and PDAC specimens. C, box plots of EZH2 and FBW7 protein expression based on their IS in PDAC specimens at different clinical stages. G1, G2, and G3 represent well differentiated, moderately differentiated, and poorly differentiated tumors, respectively. D, correlation analysis of the IS of expression levels of EZH2 and FBW7 proteins in human pancreatic cancer specimens (n = 47).