Table 2.

Disease-modifying agent attributes and levels

Attribute level	Text description
Dosage
Oral 1x/d	This drug is taken at home as a pill once a day.
Oral 2x/d	This drug is taken at home as a pill twice a day.
Inject 1/wk	This drug is taken at home by injection once a week.
Inject 1x/d	This drug is taken at home by injection once a day.
Infusion 1x/mo	This drug is given by infusion in an outpatient setting once a month.
Efficacy
Mental/emotional	This drug works best improving how you feel mentally and emotionally. You could expect an improved ability to think or remember things, and reduced depression.
Physical feeling	This drug works best improving how you feel physically. You could expect reduced fatigue, less pain, and less numbness or tingling.
Physical function	This drug works best improving how you can do things physically. You could expect better coordination, bladder or bowel control, and vision. You could also expect more ability to walk and perform activities of daily living.
Mental/emotional and physical feeling	This drug works best improving both how you feel mentally and emotionally, and how you feel physically. You could expect an improved ability to think or remember things, and reduced depression. You also could expect reduced fatigue, less pain, and less numbness or tingling.
Mental/emotional and physical function	This drug works best improving both how you feel mentally and emotionally, and how you can do things physically. You could expect an improved ability to think or remember things, and reduced depression. You could expect better coordination, bladder or bowel control, and vision. You could also expect more ability to walk and perform activities of daily living.
Physical feeling and function	This drug works best improving both how you feel physically, and how you can do things physically. You could expect reduced fatigue, less pain, and less numbness or tingling. You could expect better coordination, bladder or bowel control, and vision. You could also expect more ability to walk and perform activities of daily living.
Helps all domains	This drug works well in all three areas, improving how you feel mentally and emotionally, how you feel physically, and how you can do things physically. You could expect an improved ability to think or remember things, and reduced depression. You could expect reduced fatigue, less pain, and less numbness or tingling. You could expect better coordination, bladder or bowel control, and vision. You could also expect more ability to walk and perform activities of daily living.
Relapse
Mild	Relapses when taking this drug tend to be mild. They can be managed at home with an oral steroid.
Moderate	Relapses when taking this drug tend to be moderate. They can be managed in an outpatient setting with an intravenous steroid.
Severe	Relapses when taking this drug tend to be severe. You would have to check into a hospital for treatment.
Side effects
Not significant	Most people experience few side effects with this drug.
Cardiopulmonary	The most common side effects with this drug affect your heart and lungs. They may include chest pain, shortness of breath, high blood pressure, or a heart rate that races, is too slow, or is uneven.
Skin reaction	The most common side effects with this drug are skin reactions. They may include flushing, redness, itching, or a rash.
Flulike symptoms	The most common side effects with this drug are flulike symptoms. They may include fatigue, nausea, vomiting, diarrhea, muscle aches, or abdominal pain.
Neurologic	The most common side effects with this drug affect your nervous system. They may include vision changes, changes in thinking or memory, depression, numbness in hands or feet, or a weakness on one side of the body.