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. 2017 Apr 7;21:16-102. doi: 10.7812/TPP/16-102

Table 4.

Marginal effects (standard errors) of changing Drug A characteristics

Variable ΔP: Drug A selected ΔP: Drug B selected ΔP: No drug selected
Marginal effect of changing dosage modality from oral 1x/d to:
Oral 2x/d −0.013 (0.025) 0.003 (0.005) 0.011 (0.020)
Injection 1x/wk −0.080 (0.021)a 0.015 (0.004)a 0.065 (0.017)a
Injection 1x/d −0.076 (0.025)a 0.014 (0.005)a 0.061 (0.020)a
Infusion 1x/mo −0.097 (0.023)a 0.018 (0.004)a 0.079 (0.019)a
Marginal effect of changing efficacy domain from improvement mentally/emotionally to:
How you feel physically 0.027 (0.029) −0.004 (0.005) −0.023 (0.024)
How you function physically 0.077 (0.025)a −0.013 (0.004)a −0.064 (0.021)a
Mentally/emotionally and how you feel physically 0.067 (0.029)b −0.011 (0.005)b −0.056 (0.024)b
Mentally/emotionally and how you function physically 0.116 (0.029)a −0.021 (0.005)a −0.096 (0.024)a
How you feel and function physically 0.068 (0.028)b −0.011 (0.005)b −0.056 (0.024)b
All three domains 0.174 (0.030)a −0.033 (0.006)a −0.141 (0.025)a
Marginal effect of changing from risk of mild relapse to:
Risk of moderate relapse −0.113 (0.020)a 0.022 (0.004)a 0.090 (0.016)a
Risk of severe relapse −0.251 (0.019)a 0.043 (0.004)a 0.207 (0.016)a
Marginal effect of changing from relatively few side effects to:
Risk of cardiopulmonary side effects −0.282 (0.029)a 0.054 (0.006)a 0.228 (0.024)a
Risk of skin-related side effects −0.129 (0.025)a 0.028 (0.005)a 0.100 (0.020)a
Risk of flulike symptoms −0.194 (0.025)a 0.040 (0.005)a 0.154 (0.020)a
Risk of neurologic side effects −0.303 (0.023)a 0.056 (0.005)a 0.247 (0.019)a
a

p < 0.01.

b

p < 0.05.

Δ = change.