Skip to main content
. 2017 Apr 14;12(4):e0175369. doi: 10.1371/journal.pone.0175369

Fig 4. IL-1β expression in WT and Tg astrocytes and cortex.

Fig 4

Tg and WT astrocytes were treated or not with pantethine, then exposed or not to oAβ. IL-1β mRNA expression was determined on cell extracts; cytokine production was assayed on cell supernatants. In cortex samples collected from mice littermates, mRNA expression and protein production were determined on tissue extracts. (A) qPCR analysis. (B) IL-1β ELISA assays. Results are the mean values ± SD from three independent experiments (n = 3 per group); (*, significant difference between Tg and WT groups; §, significant difference with the corresponding group not exposed to oAβ; #, significant difference with the corresponding group untreated with pantethine; p<0.05).