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. 2017 Apr 14;12(4):e0175794. doi: 10.1371/journal.pone.0175794

Table 4. Multivariate Cox proportional hazards model to identify clinical factors associated with incident DM among COPD patients (n = 1568).

Variables Hazard ratio 95% confidence interval p value
Comorbidity
 Hypertension 1.810 1.363–2.403 <0.001
 Cerebrovascular disease 1.517 1.146–2.008 0.004
 Coronary artery disease 1.408 1.089–1.820 0.009
Concomitant medications
 ACEI/ARB 0.903 0.688–1.187 0.465
 β blocker 1.079 0.833–1.397 0.566
 Calcium channel blocker 1.066 0.815–1.396 0.640

ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus