Pack years and comorbidity score boxplots among ever smokers. A, Overall pack years differ by comorbidity score (none, mild, moderate, severe) with an ANOVA test p-value=0.0006. B, Remote use pack years also differ by comorbidity (none, mild, moderate, severe) with an ANOVA test p-alue=0.0001. C, Recent use pack years did not differ significantly by comorbidity score (none, mild, moderate, severe) with an ANOVA test p-value=0.88. Comorbidities were associated with pack years in a monotonic trend when accounting for the intensity and duration of smoking habit.