Table 1.
Variable | SRNS (n = 20) | SSNS (n = 30) | P value |
---|---|---|---|
Age, years; mean ± SE | 12.3 ± 1.2 | 7.5 ± 0.8 | .001 |
Sex, %, male | 14 (70) | 20 (68) | NS |
Pathology, % | |||
FSGS | 16 (80) | 2 (6.7) | .001 |
MCD | 1 (5) | 7 (23.3) | |
Other | 2 (10) | 0 | |
No biopsy | 1 (5) | 21 (70) | |
Hypertension | 15 (75) | 9 (30) | .003 |
Immunosuppressant, % | |||
Steroid | 9 (45) | 26 (87) | .001 |
CNI | 4 (20) | 5 (17) | |
MMF | 3 (15) | 1 (3) | |
Rituximab | 2 (10) | 4 (13) | |
CTX | 2 (10) | 3 (10) | |
ACEI/ARB | 8 (40) | 1 (3) | |
GFR, mL/min/1.73 m2 | 119 ± 11.4 | 135 ± 6.1 | NS |
MALB/Cr, mg/mg; ± SE | 2.0 ± 0.6 | 1.5 ± 0.34 | NS |
Abbreviations: FSGS, focal segmental glomerulosclerosis; GFR, glomerular filtration rate; MCD, minimal change disease; SRNS, steroid-resistant nephrotic syndrome; SSNS, steroid-sensitive nephrotic syndrome; CNI, calcineurin inhibitor; MMF, mycophenolate mofetil; CTX, cytoxan; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; MALB, microalbumin; Cr, creatinine.