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. 2016 Jun 24;2(6):e1600708. doi: 10.1126/sciadv.1600708

Fig. 4. Absence of anatomical placodes in scaleless P. vitticeps skin.

Fig. 4

(A to C) WMISH showing the expression of early markers of epidermal appendage development in WT and Sca bearded dragon embryos at various indicated developmental stages: (A) Shh; (B) Ctnnb1; and (C) Edar (left), Eda (center), and Bmp4 (right). Left panels show the WMISH signal on the lateral skin region, and right panels show parasagittal cryosections of the corresponding regions. Insets show high magnifications of the staining and indicate the presence/absence of placode formation in WT and mutant skin, respectively.