Table 5.

The matrix of DOE predicted peptone mixtures and its effect on µ and q based on in vitro experiments

Media/Mix #	Tryptone N1from casein	Casein peptone E1	Soy peptone E110	Soy peptone A2SC	Amount of peptones mixture (g/L)	MAX.pro.production (miliunit/ml)	µ (/day)	q (micro unit/cell/day)
SFM	0	0	0	0	0	5039.06	0.84±0.001	4.83±0.006
1	0	0	27.08	72.92	5	4982.91	0.73±0.038	5.45±0.202
2	31.27	68.73	0	0	5	4836.43	0.64±0.021	5.92±0.141
3	63.09	36.91	0	0	5	4912.11	0.64±0.009	5.99±0.063
4	73.88	26.12	0	0	5	4921.88	0.71±0.033	5.51±0.183
5	81.92	18.08	0	0	5	4948.73	0.68±0.009	5.81±0.054
6	0	0	24.01	75.99	5	4809.57	0.63±0.014	5.95±0.097
7	38.95	61.05	0	0	5	4780.27	0.79±0.04	5.63±0.445
8	48.89	46.14	4.97	0	5	5146.48	0.66±0.014	6.18±0.094
9	75.52	24.48	0	0	5	4995.12	0.66±0.009	6±0.060
10	33.5	0	27	39.5	5	5085.45	0.64±0.031	6.21±0.213
11	8.76	0	0	91.24	2	4958.50	0.67±0.025	5.83±0.152
12	48.44	50.31	0.44	0.81	2	5202.64	0.68±0.013	6.1±0.086
13	67.88	31.49	0.26	0.36	2	5112.30	0.72±0.012	5.69±0.069
14	61.23	36.91	0.72	1.14	2	4985.35	0.74±0.278	5.39±0.142
15	21.16	0	0.01	78.83	2	5002.44	0.63±0.029	6.18±0.203

Values are means±SD of three independent experiments