Table 1. Summary of Spinal Cord Pathology in Dogs.
Animal | Test / Control Article | Score C | Score A+B+C+D | A Cervical +DRG | B Thoracic +DRG | C Lumbar +DRG | D Lumbar +DRG |
---|---|---|---|---|---|---|---|
543 2774 | Oxytocin | 0 | 0.75 | fibroblasts/macrophages | Un- remarkable | Un- remarkable | Un- remarkable |
502 8604 † | Oxytocin | 0.75 | 3.25 | compressed/sparse inflammation | fibroblasts/macrophages/sparse inflammation | minimal fibroblasts | minimal fibroblasts/macrophages |
542 9935 * | Oxytocin | 0.75 | 3.75 | Un- remarkable | fibroblasts/macrophages | lymphocytes/plasma cells/neutrophils/fibroblasts | fibroblasts/macrophages |
543 4297 * † | Saline | 0.75 | 1.5 | Un- remarkable | Un- remarkable | mild thickening/fibroblasts/macrophages | fibroblasts/macrophages/monocytes |
501 5219 * | Saline | 0.75 | 3.25 | thickening/fibroblasts/macrophage | fibroblasts/macrophages | focal thickening/fibroblasts | fibroblasts/macrophages |
501 5014 | Oxytocin | 1 | 2.75 | focal thickening/fibroblasts | Un- remarkable | focal thickening/fibroblasts/rare clusters macrophages/lymphocytes | multifocal fibroblasts/macrophages/ |
503 7565 * | Oxytocin | 1.25 | 5.25 | neutrophils/macrophage/lymphocytes | focal thickening/ | neutrophils/macrophages/lymphocytes/neutrophils | lymphocytes/plasma cells |
501 8501 | Saline | 2 | 6 | thickening/compressed/fibroblasts/macrophage | compressed/fibroblasts/macrophages | lymphocytes/plasma cells/macrophages | lymphocytes/plasma cells/macrophages |
543 0194 | Oxytocin | 2.25 | 10.25 | mild thickening/neutrophils/fibroblasts | mild compression/fibroblasts/macrophages | mild thickening/neutrophils/fibroblasts | mild thickening/neutrophils/fibroblasts |
502 9988 | Saline | 3 | 11 | thickening/compressed/fibroblasts/macrophage neutrophils/lymphocytes | compressed/fibroblasts/macrophages neutrophils/lymphocytes | macrophages neutrophils/lymphocytes/plasma cells/ | macrophages neutrophils/lymphocytes/plasma cells/ |
= representative hematoxylin and eosin
= representative glial fibrillary acidic protein
DRG – dorsal root ganglion