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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Anesthesiology. 2014 Apr;120(4):951–961. doi: 10.1097/ALN.0000000000000148

Table 1. Summary of Spinal Cord Pathology in Dogs.

Animal Test / Control Article Score C Score A+B+C+D A Cervical +DRG B Thoracic +DRG C Lumbar +DRG D Lumbar +DRG
543 2774 Oxytocin 0 0.75 fibroblasts/macrophages Un- remarkable Un- remarkable Un- remarkable
502 8604 Oxytocin 0.75 3.25 compressed/sparse inflammation fibroblasts/macrophages/sparse inflammation minimal fibroblasts minimal fibroblasts/macrophages
542 9935 * Oxytocin 0.75 3.75 Un- remarkable fibroblasts/macrophages lymphocytes/plasma cells/neutrophils/fibroblasts fibroblasts/macrophages
543 4297 * Saline 0.75 1.5 Un- remarkable Un- remarkable mild thickening/fibroblasts/macrophages fibroblasts/macrophages/monocytes
501 5219 * Saline 0.75 3.25 thickening/fibroblasts/macrophage fibroblasts/macrophages focal thickening/fibroblasts fibroblasts/macrophages
501 5014 Oxytocin 1 2.75 focal thickening/fibroblasts Un- remarkable focal thickening/fibroblasts/rare clusters macrophages/lymphocytes multifocal fibroblasts/macrophages/
503 7565 * Oxytocin 1.25 5.25 neutrophils/macrophage/lymphocytes focal thickening/ neutrophils/macrophages/lymphocytes/neutrophils lymphocytes/plasma cells
501 8501 Saline 2 6 thickening/compressed/fibroblasts/macrophage compressed/fibroblasts/macrophages lymphocytes/plasma cells/macrophages lymphocytes/plasma cells/macrophages
543 0194 Oxytocin 2.25 10.25 mild thickening/neutrophils/fibroblasts mild compression/fibroblasts/macrophages mild thickening/neutrophils/fibroblasts mild thickening/neutrophils/fibroblasts
502 9988 Saline 3 11 thickening/compressed/fibroblasts/macrophage neutrophils/lymphocytes compressed/fibroblasts/macrophages neutrophils/lymphocytes macrophages neutrophils/lymphocytes/plasma cells/ macrophages neutrophils/lymphocytes/plasma cells/
*

= representative hematoxylin and eosin

= representative glial fibrillary acidic protein

DRG – dorsal root ganglion