Figure 11. Rac protein knockdown suppresses the tumor progression in the mouse xenotransplantation model.
CD133+-tumorspheroid cells derived from U373-MG harboring scramble control or shRacs were injected into the NOD/SCID mouse flanks to generate the tumor. A. The average of tumor diameters in all groups. B. The diameters of each tumors were plotted by GraphPad. (The lines represent the Q1, mean, and Q3 of quartile deviation.).