Table 5. Multivariable linear regression analysis of MEG3 promoter methylation and TET2 expression.
TET2 2-ΔΔCt | B | P | 95% CI | ||
---|---|---|---|---|---|
MEG3_1_CpG_10 | Control | 0.040 | 0.593 | −0.125 | 0.204 |
Case | −0.152 | 0.040 | −0.296 | −0.008 | |
MEG3_1_CpG_24 | Control | 0.024 | 0.741 | −0.136 | 0.184 |
Case | −0.119 | 0.047 | −0.236 | −0.002 | |
MEG3_2_CpG_2 | Control | 0.059 | 0.104 | −0.015 | 0.134 |
Case | −0.091 | 0.028 | −0.171 | −0.012 | |
MEG3_5_CpG_11 | Control | 0.024 | 0.351 | −0.032 | 0.081 |
Case | −0.057 | 0.001 | −0.084 | −0.03 | |
MEG3_6_CpG_1.2.3 | Control | −0.023 | 0.213 | −0.095 | 0.049 |
Case | −0.155 | 0.048 | −0.307 | −0.002 | |
MEG3_8_CpG_2 | Control | −0.038 | 0.509 | −0.166 | 0.089 |
Case | −0.026 | 0.020 | −0.047 | −0.005 |
P < 0.05 indicates statistical significance; 95% CI: 95% confidence interval.