| The signaling pathway network common to many RTKs and other intracellular kinases |
BRAF, PTPN11, PDGFRA, HRAS, KRAS, NRAS, NF1, KIT, TIAM1, MDM2, PIK3CA, ERBB2, FGFR4, TP53, EGFR, PTEN, NTRK1, CDKN2A/B, CDKN1C, PTPRD, MYCN, ALK, CDK4/6, CHEK2, RB1, RBMS3, CCND1, BARD1,BCOR, PINK, BRCA2, FANCA, PALB2 |
| Multiplication and apoptosis |
PTPN11, ALK, CDK4/6, CHEK2, RB1, PTEN CDKN2A/B PTPRD, CDKN1C, MYCN, RBMS3 |
| DNA repair |
BRCA2, FANCA, CHEK2, PALB2 |
| cancer cell transfer and angiogenesis |
TIAM1, RBMS3 |
| Embryonic development related signaling pathway |
APC AXIN2 CTNNB1, FBXW7, PHOX2B, OS9 GLI1 PTCH1, LMO1 |
| Signaling by WNT |
APC AXIN2 CTNNB1 |
| Signaling by NOTCH |
PHOX2B, FBXW7, TP53, CCND1 |
| Signaling by Hedgehog |
PTCH1, OS9, GLI1 |
| The possible genes related to MYCN |
ALK, LIN28, ODC1, CDK4, MDM2 , DDX1, NAG and other molecules downstream/upstream of MYCN in MYCN-related signaling pathways |
| Chromatin remodeling |
ARID1A/B, ATRX |
