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. 2017 Jan 3;8(11):18456–18485. doi: 10.18632/oncotarget.14472

Figure 2. Hypotheses potentially explaining the association between diabetes and colorectal cancer.

Figure 2

Two major potential relationships have been depicted. A. Common risk factors (e.g. diet, genetic) favor both diabetes and colorectal cancer; B. Diabetes favors cancer development. These potential relationships are put in context with the occurrence of other diabetes complications such a chronic kidney disease. Obesity is a known risk factor for both colorectal cancer and diabetic kidney disease.