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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Osteoporos Int. 2017 Feb 7;28(5):1507–1529. doi: 10.1007/s00198-016-3894-y

Table 1.

Statistically significant findings (p<0.05) of Cochrane systematic reviews for secondary fracture prevention with oral bisphosphonates for postmenopausal women

Treatment Hip fracture reduction (%) Vertebral fracture reduction (%) Non-vertebral fracture reduction (%) Reference
RRRa
(95% CIc)
ARRb RRR (95% CI) ARR RRR (95% CI) ARR
Alendronated 53 (15-74) 1 45 (31-57) 6 23 (8-36) 2 Wells et al [11]
Etidronatee - - 47 (13-68) 5 - - Wells et al [12]
Risedronatef 26 (6-41) 1 39 (24-50) 5 20 (10-28) 2 Wells et al [13]
a

RRR = Relative Risk Reduction

b

ARR = Absolute Risk Reduction

c

CI = Confidence Interval

d

10 mg daily dose

e

400 mg daily dose

f

5 mg daily dose