Table 4. Associations of categories for sedentary time and physical activity with adiposity indicators.

	BMI (kg/m2) (n=333; obs=526)		Waist circ. (cm) (n=310; obs=457)		Sum of skinfolds (mm) (n=156; obs=156)
	β (95% CI)	p	β (95% CI)	p	β (95% CI)	p
Model 1
Sedentary time	-0.0069 (-0.040 to 0.027)	0.69	0.056 (-0.075 to 0.19)	0.40	0.21 (-0.12 to 0.53)	0.21
Light PA	-0.00021 (-0.043 to 0.042)	0.99	-0.056 (-0.22 to 0.11)	0.51	-0.059 (-0.47 to 0.35)	0.78
MVPA	0.045 (-0.040 to 0.13)	0.30	-0.14 (-0.46 to 0.19)	0.41	-0.76 (-1.4 to -0.085)	0.027
Total PA (cpm)	0.042 (-0.037 to 0.12)	0.30	-0.072 (-0.39 to 0.24)	0.65	-0.64 (-1.46 to 0.19)	0.13
Model 2 – Isotemporal substitution
ST → Light PA	-0.0096 (-0.055 to 0.036)	0.68	-0.034 (-0.21 to 0.15)	0.71	0.048 (-0.37 to 0.47)	0.82
ST → MVPA	0.052 (-0.039 to 0.14)	0.27	-0.11 (-0.46 to 0.24)	0.54	-0.77 (-1.46 to -0.084)	0.028
Light PA → MVPA	0.061 (-0.054 to 0.18)	0.30	-0.077 (-0.53 to 0.37)	0.74	-0.82 (-1.71 to 0.062)	0.068

Statistical analyses performed using multilevel models adjusted for age, gender, ethnicity, index of multiple deprivation, monitor wear time (not in models with total PA as the outcome), and season of assessment. Models with waist circumference and sum of skinfolds as the outcomes were further adjusted for height. All results are scaled to represent the association between exposures and outcomes per 20 min difference in time-based exposures and 300 total PA counts per minute. Model 2 shows isotemporal substitution results and the effect of exchanging 20 minutes of ST or PA for different PA intensities. For example, shifting 20 minutes of ST to MVPA was associated with 0.77 mm lower sum of skinfolds, and vice versa shifting 20 minutes of MVPA to ST was associated with 0.77 mm higher sum of skinfolds. Statistically significant results are in bold. CI: Confidence interval; ST: Sedentary time; PA: Physical activity; MVPA: Moderate-to-vigorous physical activity; cpm: counts per minute.