Table 4.
Distribution of virulence genes in study isolates by gender, ST69, and ST found in men
| Virulence factor/Gene | Number and(%)of
positive isolates |
pa | Number and (%) in ST
|
pb | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total N=139 | Women N=127 | Men N=12 | ST69 N=15 | ST73 N=21 | ST405 N=4 | ST131 N=3 | ST706 N=3 | ST14 N= 3 | ST699 N=1 | ST90 N=1 | |||
| Adhesin | |||||||||||||
| papA | 65 (45) | 59 (46) | 6 (50) | NS | 4 (27) | 14 (67) | 3 (75) | 0 | 3 | 3 | 0 | 0 | 0.041 |
| papG I | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| papG II | 63 (45) | 59 (46) | 4 (33) | NS | 12 (80) | 14 (67) | 3 (75) | 0 | 0 | 3 | 0 | 0 | NS |
| papG III | 17 (12) | 13 (10) | 4 (33) | NS | 2 (13) | 11 (52) | 0 | 0 | 0 | 0 | 1 | 0 | 0.04 |
| fimH | 123 (88) | 111 (87) | 12 (100) | 15 (100) | 21 (100) | 4 (100) | 3 | 3 | 3 | 1 | 1 | NS | |
| afa/draBC | 12 (9) | 12 (9) | 0 | NS | 1 (7) | 0 | 1 (25) | 1 | 0 | 0 | 0 | 0 | NS |
| sfa/focDE | 42 (30) | 34 (27) | 8 (67) | 0.02 | 1 (7) | 20 (95) | 0 | 0 | 3 | 2 | 1 | 0 | <0.001 |
| Toxins | |||||||||||||
| hlyA | 37 (27) | 30 (24) | 7 (58) | 0.03 | 0 | 16 (76) | 0 | 0 | 3 | 2 | 0 | 0 | <0.001 |
| cnf 1 | 27 (19) | 20 (16) | 7 (58) | 0.004 | 0 | 17 (81) | 0 | 0 | 0 | 0 | 0 | 0 | <0.001 |
| Siderophore | |||||||||||||
| iutA | 108 (78) | 101 (80) | 7 (58) | NS | 13 (87) | 15 (71) | 3 | 3 | 3 | 3 | 0 | 1 | NS |
| fyuA | 116 (84) | 104 (82) | 12 (100) | <0.001 | 14 (93) | 21 (100) | 3 | 3 | 3 | 3 | 1 | 1 | NS |
| Invasin | |||||||||||||
| kpsMT II | 102 (73) | 92 (72) | 10 (83) | NS | 10 (67) | 21 (100) | 3 | 3 | 0 | 3 | 1 | 0 | 0.02 |
| traT | 13 (9) | 11 (9) | 2 (17) | NS | 14 (93) | 10 (48) | 3 | 3 | 1 | 1 | 0 | 1 | 0.01 |
| ibeA | 71 (51) | 62 (49) | 9 (75) | NS | 0 | 0 | 3 | 3 | 3 | 0 | 0 | 0 | 0 |
| Pathogenicity island | |||||||||||||
| MalX | 67 (48) | 56 (44) | 11 (92) | 0.003 | 0 | 21 (100) | 3 | 3 | 3 | 3 | 1 | 0 | <0.001 |
| Virulence Score: mean; median | 6; 6 | 7; 7 | 8; 8 | NS | 5; 6 | 9; 9 | 7; 7 | 7; 7 | 9; 9 | 8; 8 | 6; 6 | 4; 4 | <0.001 |
a
p for comparison between women vs men;
b
p for comparison between ST69 and ST73.
p < 0.05 are shown in bold; NS: no significant difference (p > 0.05) ST: sequence type. ST69: isolates identified only in women. ST73, ST405, ST131, ST706, ST14; ST699 and ST90: isolates identified in women and men Virulence score: the sum of positive virulence traits, proposed by Moreno (2005)