Skip to main content
. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Pharmacol Res. 2017 Jan 25;119:89–98. doi: 10.1016/j.phrs.2017.01.024

Fig. 2. Intracellular accumulation of [3H]-MX.

Fig. 2

(A) The effect of cabozantinib on the cellular accumulation of [3H]-MX in H460, H460/MX20 cells. (B). The effect of cabozantinib on the efflux activity of ABCG2 after 30,60, and 120 min of incubation in H460 and H460/MX20 cell lines.

(C). The effect of cabozantinib on cellular accumulation of [3H]-MX in HEK293/pcDNA3.1 and ABCG2-293-R2 cells. (D). The effect of cabozantinib on the efflux activity of ABCG2 after 30,60, and 120 min of incubation in HEK293/pcDNA3.1 and ABCG2-293-R2 cell lines.