Fig. 1.
Effects of AdipoRon on injury-induced neointima formation in mouse femoral artery. AdipoRon was administered orally (50 mg/Kg) a day before femoral artery injury and for the following 21 days until sacrifice. Femoral artery sections from AdipoRon- and vehicle-treated (Control) mice were then subjected to: A) Hematoxylin and Eosin (H&E); and B) Elastic Van Gieson (EVG) staining. The arrows indicate internal and external elastic laminae; scale bars represent 100 μm. C) Morphometric analyses of injured femoral arteries that include intima/media ratio and intimal area. The data shown are the means ± SEM. * p < 0.05; n = 5 to 7 mice/group.