Table 3.

Daily water balance, Protocol 1

	Control	F	F + HS	HS	G + HS
(A) Daily water intake (mL)
Baseline	45 ± 2	41 ± 2	40 ± 2	38 ± 2	36 ± 2
Week 1	35 ± 2	41 ± 4	41 ± 2	36 ± 2	50 ± 3
% change	−22	0	3	−5	39
P‐value	0.003	n.s.	n.s.	n.s.	0.0001
Week 2	33 ± 2	45 ± 4	54 ± 3	45 ± 3	60 ± 5
% change	−6	10	32	25	54
P‐value	n.s.	0.01	0.0001	0.0006	0.01
(B) Daily urine volumes (mL)
Baseline	11.7 ± 1.4	11.9 ± 1.3	12.0 ± 1.3	12.6 ± 1.6	12.6 ± 1.4
Week 1	9.5 ± 1.3	10.1 ± 1.9	11.4 ± 1.0	12.0 ± 1.5	17.9 ± 2.4 *
Week 2	10.3 ± 1.4	14.6 ± 2.3	19.6 ± 1.6*	21.5 ± 2.5*	26.4 ± 4.2*

C, control diet group; F, 20% fructose fed group; F + HS, 20% fructose fed plus high salt (4.0%) chow; HS, rats fed the high salt rat chow; G + HS, 20% glucose fed plus high salt (4.0%) chow. *P < 0.05 versus the previous week.