Figure 4.

IL‐17A blockade leads to reduced total inflammation and eosinophil influx in the airways. (A) Expression of Ccl11, Ccl24, and Il33 measured by qRT‐PCR. (B) The % of ILC2s (Lineage⁻ CD45⁺Sca1⁺ CD90.2⁺ CD25⁺ ST2⁺) in lung of mice exposed to MSS compared with PBS. (C) The severity of the inflammatory lung response in mice that received isotype or anti‐IL‐17A 1 h before each exposure to 3 μg MSS was verified using broncho‐alveolar lavage (BAL) count. Results were pooled from two experiments; n = 6–12 mice/group. * = P ˂ 0.05.