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. 2017 Mar 31;5(7):e13163. doi: 10.14814/phy2.13163

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© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Eosinophils and mast cells are not essential for the development of MSS‐induced airway inflammation. (A) The inflammatory lung response was verified in ΔdblGATA mice after exposure to 3 μg MSS using broncho‐alveolar lavage (BAL) count and differentials. (B) Polarity of the effector response evaluated as number and the % of CD4⁺ cells expressing IFNg, IL‐13 or IL‐17A. (C) Using BAL count, the inflammatory lung response was verified in Cpa3‐cre mice after exposure to 3 μg MSS. Results were pooled from two experiments; n = 6–12 mice/group. * = P ˂ 0.05.