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. 2017 Apr 10;5(7):e13222. doi: 10.14814/phy2.13222

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© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A) AMPK Thr172 phosphorylation normalized to AMPK α2 protein content, (B) AMPK α2 protein content, (C) acetyl‐CoA carboxylase 2 (ACC2) Ser212 phosphorylation normalized to ACC2 protein content, (D) ACC2 protein content in quadriceps from fed (FED) and 24 h fasted (FAST) skeletal muscle‐specific PGC‐1α knockout (MKO) and littermate floxed controls (control) mice. Values are given as mean ± SE (n = 11). Protein and phosphorylation (phos) levels are given in arbitrary units (AU). *Significantly different from FED within given genotype (P < 0.05). #Significantly different from control within given group (P < 0.05).