Table 3.

Multiple linear regression analysis for the effect of different stimulation parameters on heart rate (HR), mean arterial blood pressure (MAP), and respiratory frequency (RF)

Parameter	ΔHR (bpm)	ΔMAP (mmHg)	ΔRF (min−1)
Intercept	−34.5 ± 6.4a	−19.7 ± 3.0a	19.0 ± 3.0a
Voltage (V)	3.75 ± 1.35b	2.08 ± 0.63b	2.14 ± 0.63a
Frequency (Hz)	−2.02 ± 0.26a	0.80 ± 0.12a	−0.58 ± 0.12a
Pulse duration (msec)	−1.26 ± 0.28a	0.09 ± 0.13 n.s.	−0.19 ± 0.13 n.s.
Proximal (1) or distal (‐1) cathode	0.24 ± 1.62 n.s.	−0.87 ± 0.75 n.s.	−0.20 ± 0.76 n.s.
Right (1) or left (‐1) VNS	9.35 ± 1.63a	1.87 ± 0.76c	−2.05 ± 0.76b

VNS, vagal nerve stimulation; n.s, not significant.

^a P < 0.001.

^b P < 0.01.

^c P < 0.05.