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Model depicting the role of LINC00672 in the p53-dependent regulation of LASP1. LINC00672 participates in the p53-mediated suppression of LASP1 via its interaction with hnRNPs. p53 could regulate LINC00672 transcription from LASP1 gene locus and then LINC00672 recruits hnRNP F/H and hnRNP K, guiding p53 binds to the p53RE of LASP1, forming a p53 regulation loop.
