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. 2017 Feb 14;292(13):5335–5348. doi: 10.1074/jbc.M117.779520

TABLE 5.

Metabolic parameters for db/db mice with insulin-resistant diabetes

Data are means ± S.E. (n = 12 mice in each group).

	db/m	db/db	db/db + SGLT-2 inhibition
Body weight (g)	30.9 ± 0.64	54.1 ± 1.02^a	56.4 ± 1.18
Food intake (g/mouse/day)	4.0 ± 0.10	7.9 ± 0.29^a	7.0 ± 0.28
Blood glucose (mg/dl)	116 ± 6.8	376 ± 19.1^a	122 ± 8.7^b
Plasma insulin (ng/ml)	1.67 ± 0.24	3.94 ± 1.67^a	3.75 ± 1.21
Plasma triglycerides (mg/dl)	64.3 ± 8.6	215.3 ± 28.7^a	100.7 ± 12.6^b
Plasma cholesterol (mg/dl)	53.4 ± 3.1	128.8 ± 14.3^a	103.3 ± 9.4
Kidney weight/body weight (×10⁻³)	6.1 ± 0.14	4.6 ± 0.23^a	4.1 ± 0.05
24-h urine ACR (mg/mmol)	258.3 ± 123.4	973.4 ± 237.4^a	390.9 ± 115.3

^a p < 0.05 versus db/m is shown.

^b p < 0.05 versus db/db is shown.