FIGURE 6.
Heart iron concentrations (excluding blood) as a function of age. Black circle, total iron; blue circles, ferritin; red circles, central doublet. Values were obtained from Table 1. The solid red line is the best-fit simulation generated assuming Equation 1. The solid blue line is the equivalent for ferritin. The solid black line is the sum of the red and blue lines. Simulations were optimized against the data by minimizing root mean square deviation. Best-fit parameters (concentrations in μm) were: [CD]newborn, 31; [CD]g, 250; KCD, 2.8 weeks; [FN]newborn, 0; [FN]g, 450; KFN, 14 weeks. Log2 numbers 0, 2, 4, and 6 refer to 1, 4, 16, and 64 weeks, respectively.