Figure 2.

VBM results for the loop task. A, Whole-brain results for positive correlation between gray matter volume and accuracy (proportion correct) in the loop task. Significant correlations were found in retrosplenial cortex, medial prefrontal cortex, anterior cingulate, vmPFC/gyrus rectus, cuneus, putamen (not shown), sylvian fissure (not shown), and lateral occipital gyrus (not shown). Whole-brain results are thresholded at voxel-wise p < 0.01, cluster correction of 333 voxels to family-wise p < 0.05. B, ROI showing the hippocampus (r = 0.165). C, D, ROI showing the RSC (left r = 0.261; right r = 0.303) and mPFC (left r = 0.273; right r = 0.239). For visualization purposes, gray matter volumes were extracted from 5-mm spheres centered on peak coordinates in our ROIs and plotted against proportion correct in the task, with regression lines and r values based on the full model. ROI thresholded at voxel-wise p < 0.05, cluster correction of 336 voxels to family-wise p < 0.05.