Skip to main content
. 2017 Mar 6;8(4):384–389. doi: 10.1021/acsmedchemlett.6b00423

Table 1. Inhibition of Compounds 3–20 toward LSD1.

compd inhibition at 10 μMa (%) compd inhibition at 10 μMa (%)
3 inactive 12 27.16
4 inactive 13 inactive
5 10.18 14 15.70
6 inactive 15 11.38
7 23.25 16 57.52
8 14.31 17 51.73
9 45.45 18 28.29
10 44.86 19 38.16
11 inactive 20 88.24
GSK2879552 IC50 = 0.041 ± 0.006 μM
a

Data are represented as inhibition % at 10 μM. All experiments were independently carried out at least three times.