. 2017 Feb 27;8(4):438–442. doi: 10.1021/acsmedchemlett.7b00030

Table 1. Activity of BRD7539 Analogues at R₁ Position against Dd2 Parasites^a.

EC₅₀ values are the mean of at least two independent experiments.

Mouse (M) and human (H) microsomal stability (% remaining after 1 h). Data were obtained from a single experiment performed in duplicate and calculated from a six-point curve over 1 h.

Table 1. Activity of BRD7539 Analogues at R1 Position against Dd2 Parasitesa.

Table 1. Activity of BRD7539 Analogues at R₁ Position against Dd2 Parasites^a.