Table 2. Biodistribution of [18F]APP-1 in H3255-Tumor-Bearing Micea.
| Injected
dose/g (%) |
||
|---|---|---|
| tissue | 1 h after injection | 3 h after injection |
| blood | 1.60 ± 0.33 | 1.12 ± 0.08 |
| heart | 1.61 ± 0.38 | 0.72 ± 0.12 |
| lung | 3.48 ± 0.51 | 1.18 ± 0.14 |
| stomach | 17.93 ± 7.12 | 3.64 ± 1.68 |
| small intestine | 44.94 ± 5.51 | 14.70 ± 4.31 |
| colon | 6.96 ± 0.61 | 59.65 ± 11.68 |
| liver | 7.86 ± 1.23 | 2.78 ± 0.38 |
| pancreas | 5.80 ± 0.78 | 1.12 ± 0.12 |
| spleen | 4.37 ± 0.50 | 1.08 ± 0.17 |
| kidney | 8.58 ± 1.25 | 2.05 ± 0.22 |
| bone | 0.81 ± 0.46 | 1.32 ± 0.40 |
| muscle | 0.63 ± 0.21 | 0.29 ± 0.06 |
| tumor (H3255) | 3.62 ± 0.87 | 3.80 ± 0.88 |
| ratios | ||
|---|---|---|
| tumor/blood | 2.25 ± 0.18 | 3.35 ± 0.66 |
| tumor/muscle | 6.15 ± 1.88 | 13.37 ± 4.02 |
| tumor/lung | 1.04 ± 0.20 | 3.21 ± 0.54 |
a
The values represent the mean ± SD (n = 5).