Table 4. Inhibition of Selected LOX(L) Enzymes.
| IC50 x/÷ SD (μM)g |
||
|---|---|---|
| 20 | BAPN, 1 | |
| hLOXL2a | 0.126 x/÷ 1.30 (5) | 0.066 x/÷ 1.25 (104) |
| hLOXL2 bloodb | 1.45 x/÷ 1.57 (4) | 0.396 x/÷ 1.38 (43) |
| hLOXL2 + BSAc | 0.19 x/÷ 1.40 (3) | 0.083 x/÷ 1.53 (40) |
| hLOX + BSAd | 5.91 x/÷ 1.84 (3) | 0.550 x/÷ 1.36 (36) |
| mLOXL2 + BSAe | 0.227 x/÷ 1.46 (3) | 0.128 x/÷ 1.29 (3) |
| rLOXL2 + BSAf | 0.136 x/÷ 1.13(3) | 0.127 x/÷ 1.15(3) |
Amplex Red assay.
a
hLOXL2.
b
hLOXL2 spiked into human blood.
c
hLOXL2 with BSA.
d
hLOX with BSA.
e
mLOXL2.
f
rLOXL2.
g
IC50 values shown as geometric mean x/÷ geometric standard deviation.