Table 1.
Performance characteristics of Genotype MTBDRplus VER 2.0 LPA for detection RMP and INH resistance and MDR-TB in smear positive direct sample, 2015
| Detection of drug resistance | MGIT R | MGIT S | LPA R | LPA S | Sensitivity% | Specificity% | PPV% | NPV% |
|---|---|---|---|---|---|---|---|---|
| (95%* CI) | (95%* CI) | (95%* CI) | (95%* CI) | |||||
| *RMP | 34 | 38 | 34 | 38 | 88.2 (72.6–96.7) | 89.5 (75.2–97.1) | 88.2 (72.6–96.7) | 89.5 (75.2–97.1) |
| *INH | 36 | 36 | 34 | 38 | 91.7 (77.5–98.3) | 97.2 (85.5–99.9) | 97.1 (84.7–99.9) | 92.1 (78.6–98.3) |
| *MDR-TB (RMP&INH) | 28 | 31 | 27 | 32 | 96.4 (81.7–99.9) | 100 (88.8–100) | 100 (87.2–100) | 96.9 (83.8–99.9) |
*RMP Rifampicin, INH Isoniazid, MDR-TB Multidrug resistant Tuberculosis, R Resistant, S Susceptible, CI Confidence Interval