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List of clinical and MRI features
| Clinical indices | MRI features |
|---|---|
| • Age at disease onset | Cortical thickness |
| • Site of disease onset | • Precentral gyri |
| • Diagnostic delay | • Paracentral gyri |
| • Disease severity ALSFRS-r | White matter • Superior corona radiata |
| • Inferior corona radiata | |
| • Anterior limbs of the internal capsule | |
| • Posterior limbs of the internal capsule | |
| • Cerebral peduncles | |
| • Genu of the corpus callosum | |
| • Body of the corpus callosum | |
| • Splenium of the corpus callosum |
