Table 2.
Reaction between dimedone and compound 1 in the presence of catalyst 5 (10 mol%)
| Solvent | Toluene | DCM | DCM | DCM | THF |
|---|---|---|---|---|---|
| Temperature (°C) | 25 | 25 | 0 | -20 | 25 |
| ee (%) | 42 | 44 | 44 | 51 | 0 |
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